 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
Cancer suppressing genes found
Cold Spring Harbor, N.Y. (UPI) Oct 12, 2009 U.S. scientists say they have discovered a group of genes that act as barriers against cancer development. Cold Spring Harbor Laboratory researchers said they used a powerful technology called RNA interference, which suppresses gene activity, to screen hundreds of candidate tumor suppressors in living mice, using small hairpin-shaped molecules that attach to specific genes and switch them off. The researchers said they discovered more than 10 genes whose deactivation accelerated the development of lymphomas -- tumors of the immune system -- in the mice. The study is said to be one of only a few RNA-based screens that have been carried out in living animals to date. In addition to finding new cancer-suppressing genes, the scientists said the screen also revealed some information about tumor growth that will impact how cancer therapies are designed. For example, they said their study showed genes that act as tumor suppressors in lymphoma do not act as tumor suppressors in certain other cancer types, such as liver carcinoma. "These findings imply that genes can act as pro- or anti-cancer genes depending on genetic or cellular context," said Professor Scott Lowe, who led the research. That suggests drugs that might inhibit the activity of a protein that is a tumor promoter in patients with one type of cancer might be dangerous to administer to patients with another type of cancer. The findings appear in the journal Cancer Cell. Share This Article With Planet Earth
Related Links Hospital and Medical News at InternDaily.com
Dancing around legislative languageWashington (UPI) Oct 6, 2009 Some say it's a "tax," while others say it's a "penalty." U.S. President Barack Obama, during a blustery exchange with ABC's George Stephanopoulos, insisted it is a "responsibility." And U.S. Sen. Olympia Snowe has proposed calling it a "defined minimum contribution." The cause of all the verbal volleyball on Capitol Hill is one section of the Senate Finance Committee's healthcare bill ... read more |
|
|
| The content herein, unless otherwise known to be public domain, are Copyright 1995-2009 - SpaceDaily. AFP and UPI Wire Stories are copyright Agence France-Presse and United Press International. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by SpaceDaily on any Web page published or hosted by SpaceDaily. Privacy Statement |
del.icio.us
Digg
Reddit
YahooMyWeb
Google
Facebook